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Head-to-head comparison

AutoGen vs Letta

Compare AutoGen and Letta side by side across pricing, features, ratings, pros, cons, best-fit use cases, and alternatives.

AutoGen logo
AutoGen
agent-frameworks

Microsoft's multi-agent conversation framework (now in maintenance mode).

Pricing
Free
Rating
—
Votes
0
Letta logo
Letta
agent-frameworks

Stateful AI agents with long-term memory (formerly MemGPT).

Pricing
Free plan
Rating
—
Votes
0

Feature comparison

Feature
AutoGen
Letta
Category
agent-frameworks
agent-frameworks
Pricing
Free
Free plan
Free plan
API access
Mobile app
Browser extension
Team collaboration
Custom training
Self-hosted option
Offline mode
Multi-language support

AutoGen pros and cons

Pioneered accessible multi-agent conversation patterns
Free and open source
Backed by Microsoft Research with strong documentation
0.4 architecture is asynchronous and more observable
In maintenance mode as of 2026, no new feature focus
Microsoft steers new projects to the Agent Framework
Multiple version lines (0.2 vs 0.4/0.7) cause confusion

Letta pros and cons

Purpose-built for the agent memory problem
Strong research pedigree (MemGPT paper)
OS-style tiered memory persists across sessions
Open-source core, free to self-host
Narrower than general agent frameworks
Often used alongside other tooling, not a full stack
Renamed from MemGPT, some older docs use old name

Which one should you choose?

Best overall signal
AutoGen

Selected using Toolglade popularity signals such as views and votes.

Best value signal
AutoGen

Selected using free-plan availability and engagement signals.

Best for

AutoGen

  • multi-agent conversations
  • research prototyping
  • code-generation agents
  • agent collaboration patterns
  • Teams already running AutoGen in production

Letta

  • developers
  • Teams that need persistent agent memory
  • Builders of long-running assistants
  • Researchers exploring stateful agents

FAQ

Is AutoGen better than Letta?

It depends on your use case. Compare category fit, pricing, feature availability, and ratings before choosing.

Which tool has a free plan?

AutoGen and Letta offer a free plan based on current Toolglade data.

Where can I find alternatives?

View AutoGen alternatives or view Letta alternatives.